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Table 1 Characteristics of main Activated Clotting Time (ACT) instruments for high-dose heparin therapy.

From: Point-of-Care Testing of Hemostasis in Cardiac Surgery

INSTRUMENT (Manufacturer)

ASSAY

ACTIVATORS

SAMPLE SIZE

SAMPLE TYPE

HEMOCHRON Series (ITC, USA)

ACT

Celite or Kaolin

2 mL

FWB

HEMOCHRON JR II and SIGNATURE (ITC, USA)

ACT+

Kaolin, silica and phospholipids

1 drop

FWB

ACT II, HEPCON HMS (Medtronic, USA)

ACT, HEMOSTATUS

Kaolin or celite

0.4 mL (×2)

FWB

RAPIDPOINT COAG (Bayer, USA)

HMT

Celite

1 drop

FWB CWB

I-STAT (ABBOTT, USA)

Celite-ACT

Celite

40 microL

FWB

COAGUCHEK PRO (Roche Diagnostics, USA)

ACT

Celite

1 drop

FWB

ACTALYKE (ARRAY

1) ACT

1) Celite or kaolin

1) 1 mL

FWB

MEDICAL, USA)

2) MAX-ACT

2) Celite, kaolin and glass cocktail

2) 0.5 mL

 

SONOCLOT (Sienco, USA)

SONACT

Celite

0.4 mL

FWB CWB

  1. ACT, activated clotting time; FWB, fresh whole blood; CWB, citrated whole blood.