Multivariate relationships between international normalized ratio and vitamin K-dependent coagulation-derived parameters in normal healthy donors and oral anticoagulant therapy patients

Table 4 Simple linear correlation coefficients between investigated coagulation parameters

	INR	Fibrinogen	APTT ratio	Factor II	Factor VII	Factor X	Protein C	Prothrombin F1+2
Fibrinogen	0.320		0.203	-0.353	-0.298	-0.345	-0.275	-0.298
APTT ratio	0.627	0.203		-0.603	-0.630	-0.600	-0.606	-0.582
Factor II	-0.955	-0.353	-0.603		0.891	0.939	0.878	0.835
Factor VII	-0.941	-0.298	-0.630	0.891		0.874	0.862	0.771
Factor X	-0.940	-0.345	-0.600	0.939	0.874		0.882	0.810
Protein C	-0.883	-0.275	-0.606	0.878	0.862	0.882		0.751
F1+2	-0.828	-0.298	-0.582	0.835	0.771	0.810	0.751

The coefficients were estimated for log-transformed data in the cohort including all 203 cases enrolled to the study (donors and patients). All coefficients were significant with at least p < 0.05.

ISSN: 1477-9560