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Table 3 Bleeding Parameter

From: Comparison of 3,000 and 5,000 IU aXa/day certoparin in the prevention of deep-vein thrombosis after total hip replacement

  3,000 IU aXa/d Certoparin (n = 247) 5,000 IU aXa/d Certoparin (n = 232) p-value
Intraoperative bleeding parameters
Bleeding events 105 120 n.s
Bleedings considered heparin-related 24 43 0.01
Transfusions 98 118 n.s.
whole blood (ml; mean ± SD) 885 ± 297 1033 ± 505 <0.001
Packed cells (ml; mean ± SD) 700 ± 392 504 ± 253 <0.001
Fresh frozen plasma (ml; mean ± SD) 617 ± 165 480 ± 234 <0.001
Drain loss (ml; mean ± SD) 333 ± 241 361 ± 266 n.s.
Other blood loss (ml; mean ± SD) 467 ± 250 225 ± 75 <0.001
Wound hematoma 4 1 n.s.
Wound oozing 130 128 n.s.
Wound revision 0 1 n.s.
Postoperative bleeding parameters*
Bleeding events 170 167 n.s.
Bleeding related discontinuation of prophylaxis 12 15 n.s.
Bleedings considered heparin-related 103 119 n.s.
Transfusions 95 101 n.s.
Evacuation of wound hematoma 7 4 n.s.
Other reoperations 5 4 n.s.
  1. *Values refer to number of patients.