Table 3 Bleeding Parameter
3,000 IU aXa/d Certoparin (n = 247) | 5,000 IU aXa/d Certoparin (n = 232) | p-value | |
|---|---|---|---|
Intraoperative bleeding parameters | |||
Bleeding events | 105 | 120 | n.s |
Bleedings considered heparin-related | 24 | 43 | 0.01 |
Transfusions | 98 | 118 | n.s. |
whole blood (ml; mean ± SD) | 885 ± 297 | 1033 ± 505 | <0.001 |
Packed cells (ml; mean ± SD) | 700 ± 392 | 504 ± 253 | <0.001 |
Fresh frozen plasma (ml; mean ± SD) | 617 ± 165 | 480 ± 234 | <0.001 |
Drain loss (ml; mean ± SD) | 333 ± 241 | 361 ± 266 | n.s. |
Other blood loss (ml; mean ± SD) | 467 ± 250 | 225 ± 75 | <0.001 |
Wound hematoma | 4 | 1 | n.s. |
Wound oozing | 130 | 128 | n.s. |
Wound revision | 0 | 1 | n.s. |
Postoperative bleeding parameters* | |||
Bleeding events | 170 | 167 | n.s. |
Bleeding related discontinuation of prophylaxis | 12 | 15 | n.s. |
Bleedings considered heparin-related | 103 | 119 | n.s. |
Transfusions | 95 | 101 | n.s. |
Evacuation of wound hematoma | 7 | 4 | n.s. |
Other reoperations | 5 | 4 | n.s. |