|
3,000 IU aXa/d
Certoparin (n = 247)
|
5,000 IU aXa/d
Certoparin (n = 232)
|
p-value
|
---|
aPPT (sec; mean ± SD)
|
Preoperatively
|
42.5 ± 13.1
|
42.3 ± 12.0
|
n.s.
|
Post-op day 1
|
49.2 ± 17.1
|
51.9 ± 18.5
|
n.s.
|
Post-op day 5
|
43.9 ± 10.9
|
45.5 ± 14.3
|
n.s.
|
Last post-op day
|
44.7 ± 19.6
|
45.0 ± 19.7
|
n.s.
|
HEPTEST (IU/ml; mean ± SD)
|
Preoperatively
|
0.16 ± 0.18
|
0.21 ± 0.29
|
0.021
|
Post-op day 1
|
0.27 ± 0.16
|
0.33 ± 0.17
|
<0.001
|
Post-op day 5
|
0.21 ± 0.12
|
0.28 ± 0.18
|
<0.001
|
Last post-op day
|
0.21 ± 0.12
|
0.29 ± 0.18
|
<0.001
|
Number of platelet counts < 100,000/μl
|
Preoperatively
|
0
|
1
|
n.s.
|
Post-op day 1
|
1
|
6
|
n.s.
|
Post-op day 5
|
3
|
0
|
n.s.
|
Last post-op day
|
1
|
1
|
n.s.
|
- *Values refer to number of patients; ** (ml; mean ± SD).