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Figure 2 | Thrombosis Journal

Figure 2

From: Development of a perfusion chamber assay to study in real time the kinetics of thrombosis and the antithrombotic characteristics of antiplatelet drugs

Figure 2

Representation of the mean ± S.E.M. of the thrombotic profiles of the blood of 7 individuals treated in vitro with saline, 2-MeSAMP (10, 100 μM) and eptifibatide (2.4 μM) in absence or presence of aspirin (325 mg/d for 3 days). A), GP IIb-IIIa antagonism (eptifibatide (μM) spiked in vitro) inhibits thrombus growth. A monolayer of platelets is found at the highest dose of eptifibatide (2.4 μM). B), Effects of 2-MeSAMP on thrombus formation. C), Effects of 2-MeSAMP on thrombus formation on an aspirin background (325 mg/d for 3 days). D), representative photomicropgraphs of the thrombotic deposits.

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