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Table 2 Thrombin generation before and after CPB with PRP and PDP (at three TF concentrations)

From: Platelet-dependent thrombography gives a distinct pattern of in vitro thrombin generation after surgery with cardio-pulmonary bypass: potential implications

 

ETP (nM.min)

Pre-operatively

Post-operatively

Change (%)

PRP (0.3 pM TF)

1505 (1160-2464)

1491 (1087-2544)

-3.9 (4; -26.1)

PDP (0.3 pM TF)

1468 (1032-1913)

970 (500-1323)

-39.6 (13.9; -61.3)

PDP (1 pM TF)

1560 (1255-1928)

1083 (742-1990)

-24.4 (18.7; -52.7)

PDP (5 pM TF)

1723 (1338-2121)

1189 (810-2335)

-30,5 (28; -52.7)

  1. Data are reported as median (min-max) of at least 8 patients (10 patients enrolled- a few missing data for technical reasons). All decreases in ETP are statistically significant. p < 0.05 when comparing ETP change with PRP to those with PDP in presence of 0.3 pM TF. ETP: Endogenous Thrombin Potential. PDP: platelet-depleted plasma, PRP: platelet-rich plasma, TF: recombinant human tissue factor.