Platelet function in the postprandial period

Thrombosis Journal

Table 2 Prevalues of the platelet function parameters examined

Parameter	NL	HC	MS	Units
count	211 ± 10	216 ± 13	217 ± 11	x10³/μl
ßTG	51.7 ± 2.2	55.6 ± 2.3	52.3 ± 2.8	pg/ml
PF4	16.6 ± 2.4	18.9 ± 2.7	18.6 ± 2.5	pg/ml
TXB₂	7.4 ± 1.3	12.8 ± 2.3*	10.7 ± 1.9*	pg/ml
PS PGI₂	0.96 ± 0.09	1.82 ± 0.51*	1.65 ± 0.22*	ng/ml
SI	2.9 ± 0.4	4.1 ± 0.6*	6.8 ± 2.2*	%
WU	0.95 ± 0.02	0.86 ± 0.04*	0.78 ± 0.06*	%
retention	88.4 ± 3.2	87.1 ± 3.7	89.0 ± 3.8	%
migration	386 ± 21	397 ± 26	391 ± 22	mm²

values in x ± SD; n = 28 each group (14 m/14 f, aged 31 – 56 years); *) p < 0.01; NL indicates normolipemics; HC, hypercholesterolemics; MS, metabolic syndrome; PS, platelet sensitivity; count, platelet count; ßTG, ß-thrombogloblin; PF4, platelet factor 4; TXB₂, thromboxane B₂; PS PGI₂, platelet sensitivity to prostaglandin I₂; SI, sedimentation index; WU, WU-test.
Only TXB₂, PS PGI₂, SI and the WU-test reveal significant differences between NL vs. HC- and MS-patients, respectively. TXB₂ and PS PGI₂ seem to be more closely related to cholesterol, SI and the WU-test to TG.

ISSN: 1477-9560