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Table 3 Summary of the suggested antithrombotic strategies arising from published studies and guidelines, applied to patients with AF undergoing PCI-S

From: Triple antithrombotic therapy in patients with atrial fibrillation undergoing coronary artery stenting: hovering among bleeding risk, thromboembolic events, and stent thrombosis

Moderate-high TE risk (CHADS2 score2) · use radial approach · use radial approach
  · prefer uninterrupted OAC (INR > 2) · prefer uninterrupted OAC (INR > 2)
  · prefer BMS (DES allowed) · consider balloon-only PCI or CABG
  · at discharge prescribe TT for 1–6 months · prefer BMS (DES to be avoided)
  · target INR to 2.0-2.5 · at discharge prescribe TT for 2–4 weeks
  · prescribe gastric protection throughout DAPT/TT ·target INR to 2.0-2.5
   · prescribe gastric protection throughout DAPT/TT
Low TE risk (CHADS2 score 0–1) · use either radial/femoral approach · prefer radial approach
· withdraw OAC · withdraw OAC
· use either BMS/DES · prefer BMS (DES allowed, preferably last generation)
· at discharge prescribe DAPT for 1–6 months · at discharge prescribe DAPT for 2–4 weeks
· prescribe gastric protection throughout DAPT · prescribe gastric protection throughout DAPT
  Low bleeding risk (HAS-BLED score 0–2) Moderate-high bleeding risk (HAS-BLED score3)