Table 3 Summary of the suggested antithrombotic strategies arising from published studies and guidelines, applied to patients with AF undergoing PCI-S
Moderate-high TE risk (CHADS2 score ≥ 2) | · use radial approach | · use radial approach |
|  | · prefer uninterrupted OAC (INR > 2) | · prefer uninterrupted OAC (INR > 2) |
|  | · prefer BMS (DES allowed) | · consider balloon-only PCI or CABG |
|  | · at discharge prescribe TT for 1–6 months | · prefer BMS (DES to be avoided) |
|  | · target INR to 2.0-2.5 | · at discharge prescribe TT for 2–4 weeks |
|  | · prescribe gastric protection throughout DAPT/TT | ·target INR to 2.0-2.5 |
|  |  | · prescribe gastric protection throughout DAPT/TT |
Low TE risk (CHADS2 score 0–1) | · use either radial/femoral approach | · prefer radial approach |
· withdraw OAC | · withdraw OAC | |
· use either BMS/DES | · prefer BMS (DES allowed, preferably last generation) | |
· at discharge prescribe DAPT for 1–6 months | · at discharge prescribe DAPT for 2–4 weeks | |
· prescribe gastric protection throughout DAPT | · prescribe gastric protection throughout DAPT | |
|  | Low bleeding risk (HAS-BLED score 0–2) | Moderate-high bleeding risk (HAS-BLED score ≥ 3) |