Skip to main content

Advertisement

Table 6 Contraindications to pharmacological TP or heparin dosage adjustment necessity †

From: Cross-sectional study of adherence to venous thromboembolism prophylaxis guidelines in hospitalized patients. The Trombo-Brit study

  Total (n=322) Medical (n=219) Surgical (n=103)
Severe renal failure (ClCreat ≤ 30 ml/min) ¥ 15 (4.7%) 14 (6.45%) 1 (1.01%)
Thrombocytopenia (<50000/mm 3 ) 21 (6.52%) 21 (9.59%) 0
CNS hemorrhage in previous 7 days 4 (1.24%) 4 (1.83%) 0
Severe liver failure 7 (2.17%) 6 (2.74%) 1 (0.97%)
Suspected or active bleeding 9 (2.8%) 9 (4.11%) 0
Known bleeding diathesis 3 (0.93%) 2 (0.91%) 1 (0.97%)
TOTAL patients with contraindications 35 (11%) 32 (14.6) 3 (2.9)
  1. TP: thromboprophylaxis, ClCreat: creatinine clearence, CNS: central nervous system.
  2. † Some patients had more than one risk factor for bleeding.
  3. ¥ Adjustments required and/or change of drug. Calculations made on 316 patients (n=217 medical group and n=99 in the surgical group).