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Table 1 Baseline characteristics for the pooled study population by anaesthesia subgroups

From: Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials

 

General anaesthesia

Neuraxial anaesthesia

Combination

Number of patients

2311

4212

1539

Female, n (%)

1406 (60.8)

2471 (58.7)

902 (58.6)

Mean age, years ± SD

64.4 ± 10.5

66.2 ± 9.7*

65.6 ± 10.2*

Mean BMI, kg/m2 ± SD

30.2 ± 5.9

28.8 ± 4.9*

30.1 ± 5.8

CrCl, mL/min

   

 Median

86.3

82.4*

82.9*

 Minimum

22.0

20.9

25.0

 Maximum

295.7

289.6

231.6

Smoker or ex-smoker, n (%)

945 (40.9)

1483 (35.2)*

650 (42.2)

Hypertension, n (%)

1353 (58.5)

2203 (52.3)*

862 (56.0)

>75 years, n (%)

315 (13.6)

746 (17.7)*

266 (17.3)*

<50 CrCl, n (%)

156 (6.8)

341 (8.1)

126 (8.2)

>75 years or <50 CrCl, n (%)

371 (16.1)

870 (20.7)*

299 (19.4)*

  1. SD, standard deviation; BMI, body mass index; CrCl, creatinine clearance.
  2. *p < 0.05 when compared to general anaesthesia treatment arm.