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Table 1 Baseline characteristics for the pooled study population by anaesthesia subgroups

From: Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials

  General anaesthesia Neuraxial anaesthesia Combination
Number of patients 2311 4212 1539
Female, n (%) 1406 (60.8) 2471 (58.7) 902 (58.6)
Mean age, years ± SD 64.4 ± 10.5 66.2 ± 9.7* 65.6 ± 10.2*
Mean BMI, kg/m2 ± SD 30.2 ± 5.9 28.8 ± 4.9* 30.1 ± 5.8
CrCl, mL/min    
 Median 86.3 82.4* 82.9*
 Minimum 22.0 20.9 25.0
 Maximum 295.7 289.6 231.6
Smoker or ex-smoker, n (%) 945 (40.9) 1483 (35.2)* 650 (42.2)
Hypertension, n (%) 1353 (58.5) 2203 (52.3)* 862 (56.0)
>75 years, n (%) 315 (13.6) 746 (17.7)* 266 (17.3)*
<50 CrCl, n (%) 156 (6.8) 341 (8.1) 126 (8.2)
>75 years or <50 CrCl, n (%) 371 (16.1) 870 (20.7)* 299 (19.4)*
  1. SD, standard deviation; BMI, body mass index; CrCl, creatinine clearance.
  2. *p < 0.05 when compared to general anaesthesia treatment arm.