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Table 2 Effect of type of anaesthesia on outcomes: event rates observed with the different types of anaesthesia in the overall study population

From: Type of anaesthesia and the safety and efficacy of thromboprophylaxis with enoxaparin or dabigatran etexilate in major orthopaedic surgery: pooled analysis of three randomized controlled trials

Outcome

General anaesthesia

Neuraxial anaesthesia

Combination

Major VTE and VTE-related mortality

4.2%*

3.1%*

3.1%

(73/1731)

(101/3305)

(35/1147)

MBE

1.2%

1.4%

1.2%

 

(27/2311)

(59/4212)

(19/1539)

MBE/CRBE

4.9%

5.6%

5.7%

 

(114/2311)

(237/4212)

(88/1539)

  1. *Only significantly different odds ratio (general versus neuraxial): 1.40 (95% confidence interval: 1.03–1.90, p = 0.035); all other comparisons are not significant.
  2. VTE, venous thromboembolism; MBE, major bleeding event; CRBE, clinically relevant bleeding events.