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Table 3 Suitable laboratory tests for rivaroxaban and clinical situations

From: Laboratory assessment of rivaroxaban: a review

Chromogenic anti-Factor Xa assay Prothrombin time test
(with rivaroxaban calibrators) (with rivaroxaban-sensitive reagent)
• Acute renal failure • Emergency situations when an anti-Factor Xa assay is not available
• Bleeding complications or thrombosis during treatment
• Emergency situations (if available in time):  
   Prior to urgent surgery
   Life-threatening bleeding
   Stroke (if fibrinolytic treatment indicated)
   Acute percutaneous coronary intervention (if heparin bolus indicated)
• Overdose
• Suspected accumulation of drug