| Chromogenic anti-Factor Xa assay | Prothrombin time test |
|---|---|
| (with rivaroxaban calibrators) | (with rivaroxaban-sensitive reagent) |
| • Acute renal failure | • Emergency situations when an anti-Factor Xa assay is not available |
| • Bleeding complications or thrombosis during treatment | |
| • Emergency situations (if available in time): | |
| Prior to urgent surgery | |
| Life-threatening bleeding | |
| Stroke (if fibrinolytic treatment indicated) | |
| Acute percutaneous coronary intervention (if heparin bolus indicated) | |
| • Overdose | |
| • Suspected accumulation of drug |