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Table 2 Base case results

From: Dabigatran versus warfarin under standard or pharmacogenetic-guided management for the prevention of stroke and systemic thromboembolism in patients with atrial fibrillation: a cost/utility analysis using an analytic decision model

Option

Major bleeds/100 person-year

Major TE/100 person-year

Cost/patient (CAD $)

QALY/patient

Cost/QALY

∆ Cost

CAD $

∆ QALY

ICUR

Standard warfarin* dosage

3.21

2.12

7 289

3.5368

2061

   

Pharmacogenetic oriented warfarin dosage

3.09

2.126

7 749

3.5453

2186

460

0.0085

Dominated

Dabigatran 150 mg BID

2.872

1.813

8 494

3.7897

2241

745

0.2444

4 765

  1. *Less costly option.