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Table 3 Fibrinolytic activity of wild-type (WT) and mutant mPlm

From: Purification and characterization of mutant miniPlasmin for thrombolytic therapy

conc. (mg/mL) Digestion area (mm2)*
  WT K698N K698Q
0.05 125.7 ± 4.2 126.7 ± 8.5 71.1 ± 10.6
0.1 194.9 ± 8.8 151.8 ± 9.3 100.8 ± 20.1
0.2 217.9 ± 16.6 189.9 ± 1.7 138.0 ± 13.2
0.4 279.1 ± 2.1 233.8 ± 9.6 182.9 ± 18.6
0.8 308.1 ± 22.0 268.8 ± 4.1 203.7 ± 10.7
  1. *Area at each data point was calculated (A = πr2) by measuring the radius ® of the digestion ring.