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Table 3 Fibrinolytic activity of wild-type (WT) and mutant mPlm

From: Purification and characterization of mutant miniPlasmin for thrombolytic therapy

conc. (mg/mL)

Digestion area (mm2)*

 

WT

K698N

K698Q

0.05

125.7 ± 4.2

126.7 ± 8.5

71.1 ± 10.6

0.1

194.9 ± 8.8

151.8 ± 9.3

100.8 ± 20.1

0.2

217.9 ± 16.6

189.9 ± 1.7

138.0 ± 13.2

0.4

279.1 ± 2.1

233.8 ± 9.6

182.9 ± 18.6

0.8

308.1 ± 22.0

268.8 ± 4.1

203.7 ± 10.7

  1. *Area at each data point was calculated (A = πr2) by measuring the radius ® of the digestion ring.
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Thrombosis Journal

ISSN: 1477-9560

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