Table 3 ROC-analysis of TG-derived parameters for the detection of previous thrombosis in samples from patients preselected by LAC Screen ratio (LAC screen ratio >= 1.2 and LAC screen ratio < 1.2)
TG-derived parameter | ROC (95% CI) (LAC-S ratio >=1.2) N = 29 | Cases excluded | ROC (95% CI) (LAC-S ratio <1.2) N = 34 | Cases excluded |
|---|---|---|---|---|
dRVVT | 0.46 (0.24 - 0.68) | none | Not calculated | Not determined |
RC-low lag time | 0.76 (0.56 - 0.97) | 2 thrombosis 1 non-thrombosis | 0.59 (0.36 - 0.82) | 1 thrombosis |
RC-low peak height of thrombin formation | 0.80 (0.57 - 1.00) | 2 thrombosis 1 non-thrombosis | 0.51 (0.30 - 0.72) | 1 thrombosis |
RC-low time to peak | 0.80 (0.58 - 1.00) | 2 thrombosis 1 non-thrombosis | 0.50 (0.27 - 0.73) | 1 thrombosis |
RC-low AUC | 0.81 (0.57 - 1.00) | 2 thrombosis 1 non-thrombosis | 0.57 (0.35 - 0.78) | 1 thrombosis |
RC-high lag time | 0.83 (0.68 - 0.98) | 2 thrombosis | 0.72 (0.53 - 0.91) | 1 thrombosis |
RC_high peak height of thrombin formation | 0.82 (0.60 - 1.00) | 2 thrombosis | 0.61 (0.39 - 0.83) | 1 thrombosis |
RC_high time to peak | 0.80 (0.61 - 0.99) | 2 thrombosis | 0.70 (0.50 - 0.90) | 1 thrombosis |
RC-high AUC | 0.83 (0.60 - 1.00) | 2 thrombosis | 0.67 (0.46.- 0.87) | 1 thrombosis |