Table 1 Inclusion and exclusion criteria for donors
Inclusion criteria for clopidogrel donors | Inclusion criteria for age matched control donors | Exclusion criteria |
|---|---|---|
Clopidogrel or clopidogrel and aspirin use for at least 14Â days prior to blood draw | No clopidogrel use for at least 14Â days prior to blood draw | History of diabetes, renal failure, acute or chronic liver disease, including acute or chronic hepatitis or cirrhosis |
If on aspirin, daily aspirin dosage of at least 75Â mg/day | No aspirin use for at least 14Â days prior to blood draw | Positive for HIV, hepatitis B, or hepatitis C |
Males and Females | Males and Females | Use of Selective Serotonin Re-uptake Inhibitors (SSRIs), Seritonin-Norepinepherin Re-uptake Inhibitors (SNRIs), Omeprazole (which interferes with clopidogrel metabolism) [25], or oral anticoagulants (Coumadin, Warfarin, etc.) |