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Table 2 Parameters of coagulation, aggregation and fibrinolysis in non-DVT and DVT groups before or after TKA

From: Enhanced pre-operative thrombolytic status is associated with the incidence of deep venous thrombosis in patients undergoing total knee arthroplasty

 

Before TKA

After TKA

 

Non-DVT

DVT

p value

Non-DVT

DVT

p value

PT (sec)

11.4 ± 0.7

11.4 ± 0.6

0.938

11.9 ± 0.6

12.3 ± 0.7†

0.088

PT (%)

99.2 ± 14.6

98.0 ± 11.8

0.825

87.0 ± 21.8*

82.9 ± 10.3†

0.568

PT (INR)

1.01 ± 0.07

1.01 ± 0.05

0.984

1.04 ± 0.07

1.09 ± 0.06†

0.078

APTT (Sec)

27.2 ± 3.0

26.9 ± 1.8

0.793

28.1 ± 3.6

28.2 ± 2.1

0.926

Platelets (104/μl)

24.2 ± 7.9

23.3 ± 6.2

0.750

22.4 ± 7.5

21.4 ± 5.5

0.686

ADP2.5 (%)

56.1 ± 16.5

53.0 ± 16.7

0.645

52.6 ± 17.1

50.5 ± 13.6

0.746

ADP5.0 (%)

71.2 ± 14.6

69.2 ± 17.3

0.746

65.3 ± 13.2

68.3 ± 13.9

0.575

ADP10.0 (%)

81.3 ± 17.5

79.7 ± 14.4

0.810

74.8 ± 16.3

73.9 ± 29.2

0.919

Col1.0 (%)

47.8 ± 30.4

49.0 ± 23.0

0.905

35.1 ± 29.1

25.3 ± 25.9

0.384

FDP (μg/ml)

4.7 ± 2.0

4.4 ± 1.3

0.671

5.3 ± 2.5

5.2 ± 2.3

0.953

D-dimer (μg/ml)

1.3 ± 1.0

1.0 ± 0.5

0.301

2.2 ± 1.8*

3.0 ± 2.5†

0.311

  1. ADP2.5, ADP5.0, ADP10.0; Platelet aggregation-induced by ADP (2.5, 5.0 and 10.0 μg/ml, respectively). Col1.0; platelet aggregation-induced by collagen (1.0 μg/ml). *; p < 0.05 vs non-DVT group before surgery, †; p < 0.05 vs DVT group before surgery.