Table 4 Multivariate binary logistic regression analysis of factors associated with bleeding complications

Yes

No

P-value

OR (95% CI)

Sex

Male

11

43

1

Female

11

67

0.38

2.13 (0.38-11.82)

Residence

Urban

14

63

1

Rural

8

48

0.15

3.76 (0.60-23.47)

Age

15-39

11

62

1

40-64

8

36

0.75

0.72 (0.09-5.49)

65 and above

3

13

0.07

0.08 (0.05-1.31)

Warfarin dose

2.5 mg

3

22

1

5 mg

14

64

0.44

0.40 (0.04-4.15)

7.5 mg

3

19

0.77

1.63 (0.06-43.75)

≥10 mg

2

6

0.20

0.11 (0.00-3.19)

Duration of treatment

<1 month

2

18

1

1-3 months

8

49

0.83

1.39 (0.07-27.99)

>3 month

12

44

0.66

1.98 (0.09-42.18)

Number of drugs

<3

6

20

1

3-5

8

27

0.99

1.03 (0.02-55.25)

6-8

4

36

0.16

2.7 (0.68-10.71)

>8

4

28

0.29

2.10 (0.52-8.42)

Number of interactions

<2

7

25

1

2-4

9

62

0.92

0.82 (0.02-41.11)

≥5

6

24

0.24

0.05 (0.00-7.13)

Type of interaction

Moderate

13

54

1

Major

9

56

0.39

1.52 (0.60-3.80)

INR value

<5

2

95

1

≥5

20

16

0.00*

0.03 (0.00-0.46)