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Table 4 Multivariate binary logistic regression analysis of factors associated with bleeding complications

From: Drug-drug interactions and risk of bleeding among inpatients on warfarin therapy: a prospective observational study

Characteristics Bleeding Multivariate
  Yes No P-value OR (95% CI)
Sex Male 11 43   1
Female 11 67 0.38 2.13 (0.38-11.82)
Residence Urban 14 63   1
Rural 8 48 0.15 3.76 (0.60-23.47)
Age 15-39 11 62   1
40-64 8 36 0.75 0.72 (0.09-5.49)
65 and above 3 13 0.07 0.08 (0.05-1.31)
Warfarin dose 2.5 mg 3 22   1
5 mg 14 64 0.44 0.40 (0.04-4.15)
7.5 mg 3 19 0.77 1.63 (0.06-43.75)
≥10 mg 2 6 0.20 0.11 (0.00-3.19)
Duration of treatment <1 month 2 18   1
1-3 months 8 49 0.83 1.39 (0.07-27.99)
>3 month 12 44 0.66 1.98 (0.09-42.18)
Number of drugs <3 6 20   1
3-5 8 27 0.99 1.03 (0.02-55.25)
6-8 4 36 0.16 2.7 (0.68-10.71)
>8 4 28 0.29 2.10 (0.52-8.42)
Number of interactions <2 7 25   1
2-4 9 62 0.92 0.82 (0.02-41.11)
≥5 6 24 0.24 0.05 (0.00-7.13)
Type of interaction Moderate 13 54   1
Major 9 56 0.39 1.52 (0.60-3.80)
INR value <5 2 95   1
≥5 20 16 0.00* 0.03 (0.00-0.46)
  1. *Statistically significant association.