Incidence of venous thromboembolism in northern Sweden (VEINS): a population-based study

Thrombosis Journal

Table 3 Comparison of seven studies that reported VTE incidence by age group

	Present study	Næss et al.[2]	Braekkan et al.[3]	Oger[6]	Silverstein et al.[7]	Spencer et al.[8, 16]
Patients with first-time DVT and/or PE included	267	740	327	464	444	1567
Period of data collection	2006	1995-2001	1994-2007	1998-1999	1986-1990	1999, 2001, 2003
Geographic location	Sweden	Norway	Norway	France	United States	United States
Age at DVT and/or PE diagnosis, years^a	70 ± 15	73 (22-102)	N/A	N/A	N/A	64.6
Age groups included	≥18 years	≥20 years	>24 years	All ages	All ages	All ages
Yearly incidence of first-time DVT and/or PE^b	130	143	140	136	96^c	114^f
Incidence of first-time DVT and/or PE by age group^b (age range, years)	54 (18-64)	63 (20-64)	54 (<50)	39 (<60)	55 (15-64)^d	58 (<65)
	270 (65-74)	252 (65-74)	254 (50-69)	354 (60-74)	356 (65-74)^d	336 (65-74)
	463 (75-84)	529 (75-84)	570 (≥70)	895 (≥75)	628 (75-84)^d	538 (75-84)
	668 (≥85)	680 (≥85)			818 (≥85)^d	781 (≥85)
Yearly incidence of first-time DVT and/or PE in men^b	119	128	151	114	107^e	103
Yearly incidence of first-time DVT and/or PE in women^b	142	158	131	149	88^e	124
Yearly incidence of first-time DVT ^b	64	93	91	87	49^c	95^g
Yearly incidence of first-time PE^b	66	50	50	46	47^c	34^h

VTE = venous thromboembolism, DVT = deep vein thrombosis, PE = pulmonary embolism, N/A = data not available.
^a = Mean age with standard deviation or median age with age range, according to each study.
^b = Incidence per 100,000 person years.
^c = Incidence age- and sex adjusted.
^d = Incidence for each age group calculated as follows: The total number of female residents in the age group was calculated as: x = number of cases in females/the incidence in females. The total number of male residents in the age group was calculated as: y = number of cases in males/the incidence in males. Then, the incidence = the total number of cases in the age group/(x + y).
^e = Incidence age adjusted.
^f = Age-adjusted VTE incidence rate, all events included.
^g = Age-adjusted DVT incidence rate with or without concurrent PE.
^h = Age-adjusted PE incidence rate with or without concurrent DVT.

ISSN: 1477-9560