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Table 6 Sensitivity and specificity of ex vivo coronary artery MRI at spin echo (TE = 50 ms) and T2 image (panel on right). Different artery atheroma features are represented with reference to coronary artery image for distinct tissue components and corresponding T2 parametric image (A) of coronary endarterectomy specimen and right postsegmented image (B) showing different signal intensities (CV %) and their relative appearance on gray scale with varying T2 ranges for different atheroma components.

From: MRI of coronary artery atherosclerosis in rabbits: Histopathology-MRI correlation and atheroma characterization

Atheroma features

Signal intensity (CV %)

Sensitivity (%)

Specificity (%)

T2-wt (TE = 50 ms)

Calcium

Dark

100

100

Dark

Collagen

14.5(18 %)

95

85

Bright

Lipids

23.0(7.5 %)

90

75

Dark

Lipid core

27.5(7.5%)

100

100

Gray

Fibrous

35.5 (7 %)

85

90

Bright

Elastin

40.7 (13.5 %)

70

80

Gray