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Table 1 Summary of rFVIIa treated cardiac surgery patients (CSP) who survived >4 hours

From: Recombinant activated factor VII (rFVIIa) as salvage treatment for intractable hemorrhage

P# Age sex Procedure Co-morbidities Response to rFVIIa Outcome
    CPB EF% Pre rFVIIa Post rFVIIa  
      R P F C R P F C  
1 75M CABG - >45 18 18 8 10 0 4 0 0 Survived
13 36M Aortic arch repair + >45 28 18 16 10 6 19 20 10 Died
14 64M Aortic dissection - >45 39 37 32 50 2 6 4 0 Survived
17 63M AVR/MVR repair - <25 7 18 16 15 1 12 6 0 Survived
18 70M CABG + >25 6 20 20 20 0 0 0 0 Survived
20 72M CABG - >25 21 12 10 0 0 0 0 0 Survived
24* 79M CABG + >25 10 12 12 10 5 4 4 0 Died
27* 64M CABG, IVAD + <25 30 30 33 20 28 16 28 20 Died
30 85M CABG, ruptured aorta + >45 13 12 6 10 3 6 8 0 Died
32* 83M CABG + >25 5 18 18 10 6 18 20 0 Died
33 78F Ruptured aorta + <25 14 18 20 20 3 12 6 0 Died
35* 54M Aortic arch repair + >45 9 6 18 10 15 24 12 20 Survived
Average 17 18 18 15 6 10 9 4  
P value      .009 .038 .009 .03  
  1. P: Patient
  2. R: Red Blood Cell; P: Platelet; F: Fresh Frozen Plasma; C: Cryoprecipitate
  3. M: Male; F: Female
  4. CPB: Cardiopulmonary Bypass
  5. EF: Left Ventricular Ejection Fraction
  6. CABG: Coronary Artery Bypass Graft
  7. AVR: Aortic Valve Replacement
  8. MVR: Mitral Valve Replacement
  9. IVAD: Intraventricular Assisted Device
  10. * Patient continued to require blood transfusion past 24 hours post rFVIIa treatment.