(a) Effect of chronic aspirin treament in the NCD (no sign of cardiac disease), NSTEMI (non ST elevation myocardial infarction) and STEMI (ST elevation myocardial infarction) groups measured as closure time with the EPI-collagen cartridge. (b) Effects of aspirin in the NCD, NSTEMI and STEMI groups measured as closure time with the ADP-collagen cartridge. White bars: no aspirin treatment, black bars: aspirin treated patients. Values are expressed as mean values ± SD, *** p < 0.001, * p < 0.05, n.s. = not significant, compared to NCD. Lower values indicate increased platelet activation.