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Table 1 Demographic and clinical characteristics of the patients described

From: Catheter-related septic thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials

Case 1 2 3
Gender F F F
Age 59 42 57
Cancer site Ovarian (relapse) Breast stage III-B Ovarian stage IV
Time of catheter stay (days) before symptoms 1 155 63
Thrombus site Superior vena cava Superior vena cava extended to right atrium Subclavian and yugular veins
Days of antimicrobials before thrombolysis 7 19 6
Indication for thrombolyis Persitent fever and bacteremia. Persistent fever and septic embolization Persitent fever and septic embolization
Staphylococcus aureus methicillin sensible + + +
Streptokinase dose 250,000 IU hr. bolus + 40,000 us/hr for 24 hrs. 250,000 IU us/hr bolus. 250,000 us 1 hr. bolus + 25,000 us/hr for 12 hrs.
Thrombus lysis 100% 100% 100%
ARDS* No No No
  1. * Acute respiratory distress syndrome