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Table 1 Expression of important laboratory findings

From: Adrenal failure followed by status epilepticus and hemolytic anemia in primary antiphospholipid syndrome

Variable

Day 1

Day 5

Day 10

Day 15

Day 25

Day 50

12 month

Normal range

IgG anti-cardiolipin antibody (GPL-U/ml)

 

44.7

 

21

60.2

30.7

37.7

<12

Lupus anticoagulant

 

positive

 

positive

positive

positive

positive

absent

Anti-β-2-Glycoprotein 1 (U/ml)

   

2

6

3

negative

<5

Anti-Phosphatidylserin (U/ml)

   

72.8

10.8

31.1

 

<15

Anti-Phosphatidylethanolamin (U/ml)

   

45.2

23.9

18.5

 

<15

Antinuclear antibodies

  

negative

   

negative

absent

ENA

  

negative

    

absent

Double strand-DNA

  

negative

    

absent

anti-adrenal-antibodies

  

negative

    

absent

Cortisol 0800 h

 

26

1.1

22

 

28

 

6–26

Renin activity

  

100

    

<3β

ACTH (pg/ml)

  

468

    

<50

Aldosteron (pg/l)

  

<10

    

12–125

DHEA-sulfate (g/dl)

  

<10

    

<280

Bleeding time (min)

 

10.55

5.30

    

<7

Partial thromboplastin time (s)

39

37

48

57

58

36

41

<35

Prothrombin time (%)

64

55

55

73

78

45

36

70–100

Sodium (mmol/l)

134

140

111

139

142

143

136

132–145

Potassium (mmol/l)

3.9

4.8

3.6

4.2

4.0

3.5

3.9

3.1–5.1

C-reactive Protein (mg/dl)

6.1

6.1

12.1

3.7

1.0

0.4

0.3

<0.5

Aspartate aminotransferase (U/l)

15

17

81

37

21

16

18

<15

Alanine aminotransferase (U/l)

20

18

67

69

40

24

22

<14

LDH (U/l)

201

 

442

309

 

256

181

<240

Creatinine (mg/dl)

0.7

0.7

1.0

0.7

0.8

0.93

0.3

0.6–1.3

β2-microglobulin (mg/dl)

 

0.18

0.27

 

0.19

  

<0.08

Hemoglobin (g/l)

13.6

11.1

7.6

10.8

11.8

12.1

12.4

11.8–16.8

Platelet count /nl

129

177

56

154

97

153

174

150–350

White cell count /nl

14.5

10.3

10.2

6.2

5.4

5.6

7.8

4.3–10.0