Table 1 Distribution of clinically and genetically relevant variables in a cohort of women at baseline of the observational period 1993 – 2003. The total number of women in this analysis is 4320, i.e. excluding 17 women with a final diagnosis of a possible/potential VTE. Deviations from this number are due to missing information
Variables | |||
|---|---|---|---|
Continuous variables | n | Mean (SD) | |
Age (years) | 4320 | 26.0 (8.6) | |
Life births, number | 1910 | 1.7 (0.8) | |
BMI§ | 4309 | 23.3 (4.1) | |
Protein C (% of normal) | 4315 | 102.4 (15.8) | |
AT (% of normal) | 4316 | 98.4 (11.3) | |
Categorical parameters | Percent (%) | ||
Own history of VTE | No | 4279 | 99.0 |
Yes | 41 | 1.0 | |
Family history | No | 3840 | 88.9 |
Yes | 480 | 11.1 | |
Age, alternative | <30 | 2843 | 65.8 |
≥ 30 | 1477 | 34.2 | |
Family history of varicous veins | No | 2395 | 55.4 |
Yes | 1925 | 44.6 | |
Family history of MI | No | 3830 | 88.7 |
Yes | 490 | 11.3 | |
BMI, alternative | <25 | 3218 | 74.7 |
≥ 25 | 1091 | 25.3 | |
Ever use of hormone replacement | No | 4031 | 93.7 |
Yes | 270 | 6.3 | |
Family history of stroke | No | 4013 | 92.9 |
Yes | 307 | 7.1 | |
Ever use of oral contraceptives | No | 346 | 8.0 |
Yes | 3973 | 92.0 | |
Education level: Abitur& | No | 3119 | 73.2 |
Yes | 1139 | 26.8 | |
Ever smoker | No | 2022 | 46.8 |
Yes | 2296 | 53.2 | |
Laboratory & genetic markers | |||
Factor V Leiden mutation1 | No | 4035 | 93.7 |
Yes | 271 | 6.3 | |
Prothrombin mutation1 | No | 4088 | 96.6 |
Yes | 142 | 3.4 | |
MTHFR1 | No | 1798 | 42.5 |
Yes | 2432 | 57.5 | |
Protein C deficiency# | No | 4117 | 95.4 |
Yes | 198 | 4.6 | |
AT deficiency# | No | 4106 | 95.1 |
Yes | 210 | 4.9 |