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Table 2 Description of the subgroup of VTE cases and non-cases regarding parameters considered in this study as potential VTE risk factors at baseline of the observation period 1993 – 2003 Only definite and probable VTEs were considered as cases in this table, i.e. possible & potential VTE were excluded. Definitions of variables see text.

From: Comparison of incidence/risk of venous thromboembolism (VTE) among selected clinical and hereditary risk markers: A community-based cohort study

  Non-cases VTE cases Total cohort
  N n (%) N n (%) N n (%)
Demographic data       
Age*: 30+ years 4286 1456 (34.0) 34 21 (61.8) 4320 1477 (34.2)
BMI*: 25+ 4275 1076 (25.2) 34 15 (44.1) 4309 1091 (25.3)
OC use: yes, ever 4285 3941 (92.0) 34 32 (94.1) 4319 3973 (92.0)
Other hormones: yes, ever 4267 267 (6.3) 34 3 (8.8) 4301 270 (6.3)
Smoking: yes, ever 4284 2278 (53.2) 34 18 (52.9) 4318 2296 (53.2)
Medical history       
Personal history of VTE*: yes 4286 37 (0.9) 34 4 (11.8) 4320 41 (1.0)
Family history of VTE*: yes 4286 470 (11.0) 34 10 (29.4) 4320 480 (11.1)
Family history of varicose veins*: yes 4286 1902 (44.4) 34 23 (67.7) 4320 1925 (44.6)
Family history of MI*: yes 4286 482 (11.3) 34 8 (23.5) 4320 490 (11.3)
Family history of stroke: yes 4286 302 (7.1) 34 5 (14.7) 4320 307 (7.1)
Laboratory & genetic markers       
FVL mutation§: yes 4273 267 (6.3) 33 4 (12.1) 4306 271 (6.3)
Prothrombin mutation§: yes 4199 140 (3.3) 31 2 (6.5) 4230 142 (3.4)
Protein C deficiency #: yes 4281 4087 (95.5) 34 30 (88.2) 4315 4117 (95.4)
AT deficiency #: yes 4282 4073 (95.1) 34 33 (97.1) 4316 4106 (95.1)
MTHFR§: yes 4199 2415 (57.5) 31 17 (54.8) 4230 2432 (57.5)
  1. § homo- and heterozygote together
  2. * significant difference between VTE cases and non-cases (p < 0.05)
  3. # definition see methods