Table 2 Description of the subgroup of VTE cases and non-cases regarding parameters considered in this study as potential VTE risk factors at baseline of the observation period 1993 – 2003 Only definite and probable VTEs were considered as cases in this table, i.e. possible & potential VTE were excluded. Definitions of variables see text.
Non-cases | VTE cases | Total cohort | ||||
|---|---|---|---|---|---|---|
N | n (%) | N | n (%) | N | n (%) | |
Demographic data | ||||||
Age*: 30+ years | 4286 | 1456 (34.0) | 34 | 21 (61.8) | 4320 | 1477 (34.2) |
BMI*: 25+ | 4275 | 1076 (25.2) | 34 | 15 (44.1) | 4309 | 1091 (25.3) |
OC use: yes, ever | 4285 | 3941 (92.0) | 34 | 32 (94.1) | 4319 | 3973 (92.0) |
Other hormones: yes, ever | 4267 | 267 (6.3) | 34 | 3 (8.8) | 4301 | 270 (6.3) |
Smoking: yes, ever | 4284 | 2278 (53.2) | 34 | 18 (52.9) | 4318 | 2296 (53.2) |
Medical history | ||||||
Personal history of VTE*: yes | 4286 | 37 (0.9) | 34 | 4 (11.8) | 4320 | 41 (1.0) |
Family history of VTE*: yes | 4286 | 470 (11.0) | 34 | 10 (29.4) | 4320 | 480 (11.1) |
Family history of varicose veins*: yes | 4286 | 1902 (44.4) | 34 | 23 (67.7) | 4320 | 1925 (44.6) |
Family history of MI*: yes | 4286 | 482 (11.3) | 34 | 8 (23.5) | 4320 | 490 (11.3) |
Family history of stroke: yes | 4286 | 302 (7.1) | 34 | 5 (14.7) | 4320 | 307 (7.1) |
Laboratory & genetic markers | ||||||
FVL mutation§: yes | 4273 | 267 (6.3) | 33 | 4 (12.1) | 4306 | 271 (6.3) |
Prothrombin mutation§: yes | 4199 | 140 (3.3) | 31 | 2 (6.5) | 4230 | 142 (3.4) |
Protein C deficiency #: yes | 4281 | 4087 (95.5) | 34 | 30 (88.2) | 4315 | 4117 (95.4) |
AT deficiency #: yes | 4282 | 4073 (95.1) | 34 | 33 (97.1) | 4316 | 4106 (95.1) |
MTHFR§: yes | 4199 | 2415 (57.5) | 31 | 17 (54.8) | 4230 | 2432 (57.5) |