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Table 3 Sensitivity, specificity and positive predictive value of HCY plasma determinationand MTHFR C677T-polymorphism in patients with ICA stenosis.

From: The screening power of methylenetetrahydrofolate reductase C677T polymorphism versus plasma homocysteine concentration in patients with stenosis of the internal carotid artery

 

Sensitivity

Specificity

Positive predictive value

HCY (cut-off 14.90 μM)*

0.27

0.94

0.82

MTHFR (CT and TT)

0.56

0.40

0.48

  1. *Cut-off value = 1.5 SD above the mean value of the control group
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Thrombosis Journal

ISSN: 1477-9560

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