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Table 2 Haemostatic parameters in pztients with BIH and controls. Values are expressed as main ± SD

From: Benign intracranial hypertension associated to blood coagulation derangements

 

Patients

Healthy Controls

P value

PT(sec)

12 ± 0,5

11,5 ± 0,8

0.18, ns

aPTT (sec)

30 ± 2,5

31,5 ± 3,4

0.09, ns

Fibrinogen (mg/dl)

340 ± 80,7

360 ± 68,2

0.32, ns

ATIII (%)

72 ± 16,5

76 ± 14,7

0.34, ns

PG (%)

80 ± 14,7

74,5 ± 15,2

0.19, ns

t-PA(ng/ml)

6,8 ± 3,7

7,5 ± 4,8

0.58, ns

PAI-l(ng/ml)

45.7 ± 12.5

8.5 ± 6.7

< 0.0001, s

FPA (ng/ml)

8.7 ± 2.5

2.2 ± 1.25

< 0.0001, s

F1+2 (nM/l)

5.7 ± 1.15

0.45 ± 0.35

0.0001, s

D-dimers (ng/ml)

375 ± 65

225 ± 75

< 0.0001, s

PC(%)

64 ± 7.5

87 ± 14.5

< 0.0001, s

PS (%)

97 ± 23

103 ± 12

0.16, ns

2IgM (UM/l)

14.5 ± 6.8

0.38 ± 0.25

< 0.0001, s

2IgG(UG/l)

22.5 ± 11.5

0.58 ± 0.30

< 0.0001, s

  1. Prothrombin Time: PT; Activated Partial Prothrombin Time: aPTT;
  2. Antithrombin: AT III, Plasminogen: PG; tissue-Plasminogen Activator; t-PA, Plasminogen Activator Inhibitor type-1: PAI-1; Fibrinopeptide-A: FPA; Prothrombin Fragment 1+2: F1+2; Protein C activity: PC; Protein S activity: PS; IgM anticardiolipin antibodies Ig M and Ig G: Aβ2IgM and Aβ2IgG; s: significant; ns: not significant.