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Table 2 Haemostatic parameters in pztients with BIH and controls. Values are expressed as main ± SD

From: Benign intracranial hypertension associated to blood coagulation derangements

  Patients Healthy Controls P value
PT(sec) 12 ± 0,5 11,5 ± 0,8 0.18, ns
aPTT (sec) 30 ± 2,5 31,5 ± 3,4 0.09, ns
Fibrinogen (mg/dl) 340 ± 80,7 360 ± 68,2 0.32, ns
ATIII (%) 72 ± 16,5 76 ± 14,7 0.34, ns
PG (%) 80 ± 14,7 74,5 ± 15,2 0.19, ns
t-PA(ng/ml) 6,8 ± 3,7 7,5 ± 4,8 0.58, ns
PAI-l(ng/ml) 45.7 ± 12.5 8.5 ± 6.7 < 0.0001, s
FPA (ng/ml) 8.7 ± 2.5 2.2 ± 1.25 < 0.0001, s
F1+2 (nM/l) 5.7 ± 1.15 0.45 ± 0.35 0.0001, s
D-dimers (ng/ml) 375 ± 65 225 ± 75 < 0.0001, s
PC(%) 64 ± 7.5 87 ± 14.5 < 0.0001, s
PS (%) 97 ± 23 103 ± 12 0.16, ns
2IgM (UM/l) 14.5 ± 6.8 0.38 ± 0.25 < 0.0001, s
2IgG(UG/l) 22.5 ± 11.5 0.58 ± 0.30 < 0.0001, s
  1. Prothrombin Time: PT; Activated Partial Prothrombin Time: aPTT;
  2. Antithrombin: AT III, Plasminogen: PG; tissue-Plasminogen Activator; t-PA, Plasminogen Activator Inhibitor type-1: PAI-1; Fibrinopeptide-A: FPA; Prothrombin Fragment 1+2: F1+2; Protein C activity: PC; Protein S activity: PS; IgM anticardiolipin antibodies Ig M and Ig G: Aβ2IgM and Aβ2IgG; s: significant; ns: not significant.