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Table 3 Mutational state frequence for FV R506Q, PT G20210A, MTHFR C677T, PAI-1 4G/5G, ACE I/D genes in patients and healhty subjects (HS).

From: Benign intracranial hypertension associated to blood coagulation derangements

Gene coagulation mutations Homozygous Wilde-type Heterozygous Homozygous Mutated
  Patients (17) HS (51) Patients (17) HS (51) Patients (17) HS (51)
FV R506Q 94% 98% 6% 2% - -
PT G20210A 94% 98% 6% 2% - -
MTHFR C677T 41% 57% 41% 31% 18% 12%
PAI-1 4G/5G 47% 30% 35% 51% 18% 19%
ACE I/D 30% 46% 47% 43% 23% 11%
  1. FV R506Q: factor V Leiden gene polimorphism
  2. PT G20210A: prothrombin G20210A gene polymorphism
  3. MTHFR C677T: Methylenetetrahydrofolate reductase C677T gene polymorphism
  4. PAI-1 4G/5G: plasminogen activator inihibitor 1 4G\5G gene polymorphism
  5. ACE I\D: angiotensin converting enzyme insertion\deletion gene polymorphism