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Table 2 APTT-based Lupus Ratio before and after the addition of polybrene and heparin. APTT-based Lupus Ratios were determined in LA-positive and LA-negative patient plasmas before and after the addition of polybrene 7.9 μg/ml and/or heparin 1.0 U/ml. APTT-based Lupus Ratio <1.05 = negative result.

From: Detection and quantification of lupus anticoagulants in plasma from heparin treated patients, using addition of polybrene

 

APTT-based Lupus Ratio median (range)

 
 

LA-positive patients n = 12

LA-negative patients n = 8

Lupus Ratio

1.29 (1.07 to 2.24)

0.99 (0.84 to 1.03)

Lupus ratio with polybrene

1.20 (1.01 to 2.19)

0.94 (0.82 to 1.00)

% change

-5.50 (-10.85 to +1.77)

-1.06 (-13.29 to +2.92)

Lupus ratio with heparin and polybrene

1.26 (1.04 to 2.22)

0.98 (0.85 to 1.00)

% change

-3.52 (-6.80 to --1.10)

-1.49 (-3.09 to +1.19)