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Table 1 Clinical conditions associated with disseminated intravascular coagulation.

From: Recent acquisitions in the pathophysiology, diagnosis and treatment of disseminated intravascular coagulation

Condition Causes
Sepsis/severe infections Gram-positive bacteria, Gram-negative bacteria, spirochetes, rickettsiae, protozoa, fungi, viruses
Trauma Polytrauma, neurotrauma, fat embolism, burns
Malignancy Solid tumors, myeloproliferative/lymphoproliferative malignancies
Obstetric complications Amniotic fluid embolism, abruptio placentae, placenta previa, retained dead fetus syndrome
Vascular disorders Large vascular aneurysms, Kasabach-Merritt syndrome
Organ destruction Severe pancreatitis, severe hepatic failure
Toxic reactions Snake bites, recreational drugs
Immunologic reactions Hemolytic transfusion reaction, transplant rejection