Table 1 Clinical conditions associated with disseminated intravascular coagulation.
Condition | Causes |
|---|---|
Sepsis/severe infections | Gram-positive bacteria, Gram-negative bacteria, spirochetes, rickettsiae, protozoa, fungi, viruses |
Trauma | Polytrauma, neurotrauma, fat embolism, burns |
Malignancy | Solid tumors, myeloproliferative/lymphoproliferative malignancies |
Obstetric complications | Amniotic fluid embolism, abruptio placentae, placenta previa, retained dead fetus syndrome |
Vascular disorders | Large vascular aneurysms, Kasabach-Merritt syndrome |
Organ destruction | Severe pancreatitis, severe hepatic failure |
Toxic reactions | Snake bites, recreational drugs |
Immunologic reactions | Hemolytic transfusion reaction, transplant rejection |