Table 2 Randomized studies of thromboprophylaxis with LMWH compared with UFH in medical patients.
From: An update on prevention of venous thromboembolism in hospitalized acutely ill medical patients
Study | Patients | LMWH | UFH | LMWH as effective as UFH?* |
|---|---|---|---|---|
Harenberg et al. 1990 [30] | Hospitalised, bedridden medical (n = 166) | Dalteparin 1500 aPTT units s.c. o.d. | 5000 IU s.c. t.i.d. | Yes |
Bergmann and Neuhart, 1996 [31] | Elderly, bedridden, acutely ill medical (n = 442) | Enoxaparin 20 mg s.c. o.d. | 5000 IU s.c. b.i.d. | Yes |
Lechler et al. 1996 [32] | Medical (n = 959) | Enoxaparin 40 mg s.c. o.d. | 5000 IU s.c. t.i.d. | Yes |
Harenberg et al. 1996 [33] | Hospitalised, bedridden medical (n = 1968) | Nadroparin 36 mg s.c. o.d. | 5000 IU s.c. t.i.d. | Yes |
Kleber et al. 2003 [34] | Severe respiratory disease or acute heart failure (n = 665) | Enoxaparin 40 mg s.c. o.d. | 5000 IU s.c. t.i.d. | Yes |