Effect of heat shock on the LPS-induced shortening of clotting time in whole blood samples. Whole blood samples, supplemented with LPS (100 μg/mL final concentration, LPS) or vehicle (CON), were incubated under heat shock conditions (2 hours at 43°C, 3 hours at 37°C) or normothermia (5 hours at 37°C). Thereafter, samples were recalcified and clotting time was determined. Results are shown as mean and standard deviation of 12 experiments per group. *: p < 0.05.