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Table 1 Baseline patient characteristics according to Glycoprotein IIIa (GP IIIa) polymorphism

From: Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting

 

GP IIIa A1/A2 genotype

 

A1/A1

(n = 690)

A1/A2

(n = 248)

A2/A2

(n = 25)

p

Demographic characteristics

    

   Male sex (%)

80.9

82.7

64

0.077

   Age (mean ± SD, years)

64.4 ± 11.2

64.4 ± 11.4

66.2 ± 10.3

0.717

   Age ≥ 65 years (%)

53.9

51.6

64

0.470

Medical history

    

   Hypertension (%)

42.0

43.1

32

0.560

   Diabetes mellitus (%)

12.3

14.1

12

0.763

   Hypercholesterolemia (%)

51.6

50.4

56

0.512

   Past or current smokers (%)

50.6

53.2

40

0.417

   Body Mass Index>25 (kg/m2) (%)

63.5

66.1

52

0.293

   Family history of CAD (%)

27.8

29.8

24

0.755

   Prior MI (%)

31.2

30.2

28

0.915

   Prior PCI (%)

13.0

15.3

0

0.065

   Prior CABG (%)

10

8.1

0

0.204

Indication for PCI

    

   Stable angina (%)

14.3

18.1

16

0.752

   Unstable angina (%)

38.3

35.9

28

 

   Acute MI (%)

29.3

27.0

32

 

   Post MI (%)

11.4

12.1

16

 

   Other (%)

4.5

5.2

8

 

Angiographic characteristics

    

   LVEF < 40% (%)

15.7

16.1

8

0.716

   Single vessel disease (%)

45.4

42.7

32

0.576

   Two-vessel disease (%)

32.2

35.5

36

 

   Three-vessel disease (%)

22.5

21.8

32

 

Therapy at inclusion

    

   ACE inhibitor (%)

32.3

33.1

44

0.481

   Beta-blocker (%)

56.1

56.0

80

0.060

   Statin (%)

35.2

33.5

32

0.864

  1. ACE, angiotensin converting enzyme; CABG, coronary artery bypass graft; CAD, coronary artery disease; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention.