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Table 3 Univariate analysis of MACE in the subgroups of the study population

From: Effect of PlA1/A2 glycoprotein IIIa gene polymorphism on the long-term outcome after successful coronary stenting

 

MACE

Subgroups

n

Survival (%)

p

Demographic characteristics

   

   Males/Females

779/184

78.8/80.6

0.631

   Age ≥ 65/< 65 years

516/447

79.4/78.6

0.622

Medical history

   

   Hypertension yes/no

405/558

77.1/80.2

0.852

   Diabetes mellitus yes/no

123/840

73.7/79.9

0.481

   Hypercholesterolemia yes/no

465/498

83.0/76.0

0.124

   Past or current smokers yes/no

491/472

76.5/81.9

0.380

   BMI ≥ 25/< 25 (kg/m2)

619/344

79.1/78.7

0.253

   Family history of MI yes/no

272/691

78.5/79.4

0.401

   Prior MI yes/no

297/666

82.0/77.9

0.292

   Prior PCI yes/no

128/835

76.3/79.6

0.988

   Prior CABG yes/no

89/874

71.3/79.9

0.564

GP III a polymorphism

   

   A1A1/A1A2/A2A2

690/248/25

78.3/80.6/91.7

0.777

Coronary artery vessels diseased

   

   Single+two-/three-vessel disease

746/217

80.2/75.3

0.109

LVEF ≥ 40%/< 40%

808/155

80.4/73.5

0.012

Therapy

   

   ACE inhibitor yes/no

316/647

69.2/81.9

0.062

   Beta-blocker yes/no

546/417

74.9/81.3

0.262

   Statin yes/no

334/629

76.5/79.2

0.770

Therapy during follow-up

   

   Statin yes/no

462/501

82.6/76.2

0.031

   ACE inhibitor yes/no

338/625

89.3/73.3

< 0.001

   Beta-blocker yes/no

580/383

86.5/69.3

< 0.001

  1. ACE, angiotensin converting enzyme; BMI, body mass index; CABG, coronary artery bypass graft; LVEF, left ventricular ejection fraction; MI, myocardial infarction; PCI, percutaneous coronary intervention.