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Figure 2 | Thrombosis Journal

Figure 2

From: Increased platelet expression of FcGammaRIIa and its potential impact on platelet reactivity in patients with end stage renal disease

Figure 2

Activation of platelets identified by surface expression of P-selectin. Patients with ESRD (n = 33) were stratified into 2 groups on the basis of median expression of FcγRIIa. Activation of platelets was quantified with the use of flow cytometry for delineation of the percentage of platelets expressing P-selectin on their surface in the absence of agonist and in response to the collagen mimetic convulxin (1 ng/ml), PAF (1 nM), ADP (0.2 μM), or thrombin (1 nM). Patients with high expression of FcγRIIa did not exhibit greater activation of platelets in the absence of agonist but did exhibit greater activation in response to each of the agonists used.

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