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Figure 4 | Thrombosis Journal

Figure 4

From: Increased platelet expression of FcGammaRIIa and its potential impact on platelet reactivity in patients with end stage renal disease

Figure 4

The correlation of platelet reactivity with expression of FcγRIIa. Activation of platelets was identified with the use of flow cytometry to delineate surface expression of P-selectin in response to exposure of the platelets to the collagen mimetic convulxin (1 ng/ml), PAF (1 nM), ADP (0.2 μM), or thrombin (1 nM). Expression of FcγRIIa was quantified with the use of flow cytometry by subtracting the MFI seen with secondary antibody alone from the MFI seen with both the primary and secondary antibody. Significant and similar, although modest correlations (r values ranging from approximately 0.4–0.6) were seen with each of the agonists used.

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