Table 3 Genetic thrombophilia markers in patients and controls
From: Deep venous thrombosis in the antenatal period in a large cohort of pregnancies from western India
Thrombophilia marker | Patients (n = 32) Number positive (%) | Controls (n = 100) Number positive (%) | RR (95% CI) | P value |
|---|---|---|---|---|
FVL Het | 4 (12.5) | 0 | 4.0 (1.8–4.5) | 0.001 |
PT G20210A | 0 | 0 | - | - |
EPCR Hets | 1 (3.13) | 1 (1) | 2.0 (0.3–3.8) | 0.392 |
MTHFR homo | 1 (3.13) | 1 (1) | 2.0 (0.3–3.8) | 0.392 |
MTHFR hetero | 6 (18.75) | 12 (12) | 1.46 (0.6–2.7) | 0.333 |
Fib β448 homo | 1(3.13) | 1(1) | 2.0 (0.3–3.8) | 0.392 |
Fib β448 hetero | 5 (15.63) | 12 (12) | 1.2 (0.5–2.5) | 0.594 |
PAI 4G/4G | 13 (40.63) | 10 (10) | 3.2 (1.8–5.1) | 0 |
4G/5G | 12 (37.5) | 61 (61) | 0.4 (0.2–0.8) | 0.020 |
5G/5G | 5 (15.63) | 29 (29) | 0.5 (0.2–1.1) | 0.132 |
PC Def | 1 (3.13) | 0 | 2.8 (0.5–4.1) | 0.223 |
P S Def | 7 (21.88) | 0 | 4.6 (2.6–5.6) | 0 |
AT III Def | 0 | 0 | - | - |