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Table 3 Proinflammatory SNPs stratified by smoking status demonstrating the number of cases and controls, and Odds Ratio, 95%CI and p-values in an age-, race-adjusted additive model.

From: Ischemic stroke risk, smoking, and the genetics of inflammation in a biracial population: the stroke prevention in young women study

Gene

rs number

Smokers

Non-Smokers

  

Cases/Controls

OR*

95% CI

p-value

Cases/Controls

OR*

95% CI

p-value

CD14

rs2569190

77/31

2.05

1.09–3.87

0.027

82/121

0.93

0.62–1.39

0.72

IL1A

rs17561

106/48

1.68

0.84–3.32

0.14

111/156

1.05

0.69–1.60

0.83

IL1R1

rs3917318

102/45

1.138

0.67–1.94

0.64

108/155

1.07

0.74–1.54

0.72

IL1B

rs3917365

99/44

1.63

0.78–3.42

0.19

105/146

1.03

0.62–1.73

0.90

IL6

rs1800797

104/43

1.28

0.66–2.46

0.46

110/155

1.05

0.67–1.64

0.83

 

rs2069830

103/45

1.63

0.48–5.58

0.43

109/155

0.30

0.11–0.82

0.019

 

rs2069832

101/45

0.69

0.35–1.35

0.28

109/152

0.80

0.51–1.26

0.34

MMP3

rs679620

103/46

0.98

0.58–1.65

0.93

110/157

1.01

0.71–1.43

0.97

  1. * Adjusted for age and race (African-American, Caucasian, and other).