Figure 4From: A new method to determine tissue specific tissue factor thrombomodulin activities: endotoxin and particulate air pollution induced disbalanceInfluence of LPS on thrombin generation triggered with additional TF (5 pM) and PL (4 μM) (open curves and bars) or without (grey curves and bars). Panel A and B: Typical thrombin generation curves recorded from normal human plasma in the presence of lung (A) or liver (B) homogenate 6 hours after LPS administration. White curve (○): control lung tissue without TF/PL. Grey curve (□): lung tissue after LPS-treatment without TF/PL. Black curve (△): lung tissue after LPS-treatment with TF/PL. Panel C and D: Lag times (C) and ETPs (D) derived from the thrombin generation curves recorded for normal human plasma in the presence of organ homogenates 6 hours after LPS administration. Bars represent mean ± SD from 6 tissue homogenates.Back to article page