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Figure 4 | Thrombosis Journal

Figure 4

From: A new method to determine tissue specific tissue factor thrombomodulin activities: endotoxin and particulate air pollution induced disbalance

Figure 4

Influence of LPS on thrombin generation triggered with additional TF (5 pM) and PL (4 μM) (open curves and bars) or without (grey curves and bars). Panel A and B: Typical thrombin generation curves recorded from normal human plasma in the presence of lung (A) or liver (B) homogenate 6 hours after LPS administration. White curve (○): control lung tissue without TF/PL. Grey curve (□): lung tissue after LPS-treatment without TF/PL. Black curve (△): lung tissue after LPS-treatment with TF/PL. Panel C and D: Lag times (C) and ETPs (D) derived from the thrombin generation curves recorded for normal human plasma in the presence of organ homogenates 6 hours after LPS administration. Bars represent mean ± SD from 6 tissue homogenates.

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