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Table 1 Characteristics of the study subjects by SCAP and SREBF-2 genotype

From: Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

   SCAP     SREBF-2   
  AA GA GG P value GG GC CC P value
Number of subjects 85 132 30   140 97 10  
Age (years) 51.9 ± 9.5 51.6 ± 9.4 55.6 ± 10.3 0.114 51.9 ± 9.3 52.9 ± 9.9 49.1 ± 11.0 0.445
BMI (kg/m2) 25.4 ± 5.1 25.4 ± 4.9 24.3 ± 4.1 0.497 25.2 ± 4.9 25.3 ± 4.7 25.1 ± 6.3 0.979
Alcohol consumption (g/day) 101.5 ± 116.4 106.5 ± 106.6 74.0 ± 68.2 0.549 110. 8 ± 110.9 91.9 ± 100.4 42.7 ± 84.2 0.340
Smoking 35 (72.9) 64 (80.0) 13 (92.9) 0.256 62 (82.7) 45 (72.6) 5 (100.0) 0.177
Hypertension 6 (13.6) 31 (46.3) 5 (38.5) 0.002 23 (32.9) 18 (36.0) 1 (25.0) 0.872
Diabetes 6 (13.6) 11 (16.4) 2 (15.4) 0.924 13 (18.6) 6 (12.0) 0 (0.0) 0.423
AMI 7 (8.2) 17 (12.9) 4 (13.3) 0.537 13 (9.3) 14 (14.4) 1 (10.0) 0.466
Thrombus 4 (4.7) 14 (10.6) 2 (6.7) 0.285 10 (7.1) 9 (9.3) 1 (10.0) 0.818
SCD 29 (34.1) 51 (38.6) 15 (50.0) 0.306 54 (38.6) 38 (39.2) 3 (30.0) 0.850
  1. Values are mean ± SD or n (%). Abbreviations: AMI, acute myocardial infarction; BMI, body mass index; MI, myocardial infarction; SCD, sudden cardiac death; Analysis by ANOVA or χ2 test