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Table 1 Characteristics of the study subjects by SCAP and SREBF-2 genotype

From: Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

  

SCAP

   

SREBF-2

  
 

AA

GA

GG

P value

GG

GC

CC

P value

Number of subjects

85

132

30

 

140

97

10

 

Age (years)

51.9 ± 9.5

51.6 ± 9.4

55.6 ± 10.3

0.114

51.9 ± 9.3

52.9 ± 9.9

49.1 ± 11.0

0.445

BMI (kg/m2)

25.4 ± 5.1

25.4 ± 4.9

24.3 ± 4.1

0.497

25.2 ± 4.9

25.3 ± 4.7

25.1 ± 6.3

0.979

Alcohol consumption (g/day)

101.5 ± 116.4

106.5 ± 106.6

74.0 ± 68.2

0.549

110. 8 ± 110.9

91.9 ± 100.4

42.7 ± 84.2

0.340

Smoking

35 (72.9)

64 (80.0)

13 (92.9)

0.256

62 (82.7)

45 (72.6)

5 (100.0)

0.177

Hypertension

6 (13.6)

31 (46.3)

5 (38.5)

0.002

23 (32.9)

18 (36.0)

1 (25.0)

0.872

Diabetes

6 (13.6)

11 (16.4)

2 (15.4)

0.924

13 (18.6)

6 (12.0)

0 (0.0)

0.423

AMI

7 (8.2)

17 (12.9)

4 (13.3)

0.537

13 (9.3)

14 (14.4)

1 (10.0)

0.466

Thrombus

4 (4.7)

14 (10.6)

2 (6.7)

0.285

10 (7.1)

9 (9.3)

1 (10.0)

0.818

SCD

29 (34.1)

51 (38.6)

15 (50.0)

0.306

54 (38.6)

38 (39.2)

3 (30.0)

0.850

  1. Values are mean ± SD or n (%). Abbreviations: AMI, acute myocardial infarction; BMI, body mass index; MI, myocardial infarction; SCD, sudden cardiac death; Analysis by ANOVA or χ2 test