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Table 2 Mean percent area of different types of atherosclerotic lesions in coronary arteries by SCAP and SREBF-2 genotype

From: Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death

  

SCAP

   

SREBF-2

  
 

AA

GA

GG

P value

GG

GC

CC

P value

 

85

132

30

 

140

97

10

 

Fatty streaks

5.75 ± 4.87

6.12 ± 5.14

4.90 ± 4.19

0.463

5.51 ± 4.21

6.60 ± 5.88

3.17 ± 2.93

0.060

Fibrotic

3.06 ± 3.29

3.40 ± 3.77

2.95 ± 3.46

0.711

3.05 ± 3.44

3.61 ± 3.82

2.01 ± 2.45

0.268

Complicated

0.68 ± 1.95

1.64 ± 4.12

1.17 ± 2.38

0.053

1.26 ± 3.83

1.26 ± 2.66

1.10 ± 1.83

0.989

Calcification

2.08 ± 3.23

2.59 ± 4.97

3.06 ± 5.68

0.542

2.63 ± 4.73

2.38 ± 4.43

1.10 ± 2.46

0.572

Stenosis

36.99 ± 23.23

37.08 ± 21.12

38.36 ± 21.76

0.956

36.10 ± 22.26

39.14 ± 21.20

34.47 ± 22.92

0.550

  1. Values are mean ± SD. Analysis by ANOVA.