Skip to main content

Table 3 Bleeding events according to CYP2C9 and VKORC1 genotype.

From: Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction

CYP2C9 genotype VKORC1 genotype N (%) Mean INR (95% C.I.) Major/minor bleeding events N (%) Occult bleeding events N (%) Total bleeding events N (%)
*1/*1 C/C 33 (31.4) 2.65 (2.45–2.84) 2 (6.1) 4 (12.1) 6 (18.2)
  C/T 28 (26.7) 2.79 (2.60–2.99) 3 (10.7) 5 (17.9) 8 (28.6)
  T/T 12 (11.4) 2.71 (2.37–3.05) 2 (16.7) - 2 (16.7)
*1/*2,*3 C/C 8 (7.6) 2.58 (2.19–2.96) - 1 (12.5) 1 (12.5)
  C/T 16 (15.2) 2.83 (2.55–3.10) 2 (12.5) 4 (25.0) 6 (37.5)
  T/T 3 (2.9) 2.87 (2.49–3.25)    
*2/*2,*3 C/C 2 (1.9) 2.30 (1.03–3.57)    
  C/T 2 (1.9) 2.15 (0.24–4.06)    
  T/T 1 (1.0) 3.50    
Total   105 (100)   9 14 23