Table 3 Bleeding events according to CYP2C9 and VKORC1 genotype.
CYP2C9 genotype | VKORC1 genotype | N (%) | Mean INR (95% C.I.) | Major/minor bleeding events N (%) | Occult bleeding events N (%) | Total bleeding events N (%) |
|---|---|---|---|---|---|---|
*1/*1 | C/C | 33 (31.4) | 2.65 (2.45–2.84) | 2 (6.1) | 4 (12.1) | 6 (18.2) |
C/T | 28 (26.7) | 2.79 (2.60–2.99) | 3 (10.7) | 5 (17.9) | 8 (28.6) | |
T/T | 12 (11.4) | 2.71 (2.37–3.05) | 2 (16.7) | - | 2 (16.7) | |
*1/*2,*3 | C/C | 8 (7.6) | 2.58 (2.19–2.96) | - | 1 (12.5) | 1 (12.5) |
C/T | 16 (15.2) | 2.83 (2.55–3.10) | 2 (12.5) | 4 (25.0) | 6 (37.5) | |
T/T | 3 (2.9) | 2.87 (2.49–3.25) | ||||
*2/*2,*3 | C/C | 2 (1.9) | 2.30 (1.03–3.57) | |||
C/T | 2 (1.9) | 2.15 (0.24–4.06) | ||||
T/T | 1 (1.0) | 3.50 | ||||
Total | 105 (100) | 9 | 14 | 23 |