Figure 1

The course of platelet count of both patients during hospitalization in association with clinical events and laboratory confirmation of HIT. Laboratory tests results at the time of the diagnosis, included increased fibrin d-dimer levels (>20 μg/ml and 4.1 μg/ml respectively; normal value <0.5 μg per milliliter) and indicated the absence of disseminated intravascular coagulation (International Normalized Ratio 1.1 and 1.0, respectively; normal range 0.9 to 1.2) without circulating nucleated red cells.