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Table 1 Population characteristics.

From: Plasma fibrinolysis is related to the degree of organ dysfunction but not to the concentration of von Willebrand Factor in critically ill patients

Parameters

Values (all patients, n = 49)

Non sepsis

n = 31

Sepsis

n = 18

p

SAPS II

52.5 (45–63)

48 (38.5–64)

54 (49.2–62)

0.21

SOFA

7 (5.7–10)

6.5 (5–9)

8 (6–10.2)

0.41

ECLT (min)

791 (609–1023)

665 (551–862)

1033 (871–1372)

< 0.001

vWF (%)

368 (293–490)

370 (289–450)

367 (294–513)

0.53

WBC (103/μl)

11 (8–14)

12.1 (8.3–14.3)

9.43 (7.7–16.3)

0.9

Haemoglobin (g/dl)

10.3 (8.7–12.2)

10.7 (9.4–12.7)

9.7 (8–11.2)

0.03

Haematocrit (%)

32.5 (27.2–37.1)

32.7 (29.3–38.5)

31.7 (25.2–33)

0.06

Activated clotting time (sec)

42 (35–48)

37.5 (32.5–45.5)

48 (45–51)

< 0.001

Fibrinogen (g/l)

4.8 (3.73–6)

4.2 (3.5–5.08)

6.1 (4.6–8.1)

0.002

Prothrombin time (%)

70 (57–77)

73 (65–82)

61 (48.5–71.2)

0.006

Platelet count (103/μl)

70.5 (57.5–77)

250 (141–290)

267 (194–322)

0.27

Total bilirubin (mg/dl)

0.62 (0.41–0.91)

0.7 (0.42–0.96)

0.58 (0.39–0.85)

0.52

C-reactive protein (mg/dl

9.37 (4.4–23.4)

6.44 (2.8–11.8)

24.5 (15.5–34.6)

< 0.001

Urea (mg/dl)

62.3 (40.05–78.15)

59 (39.6–75.1)

74 (44–78)

0.27

Creatinine (mg/dl)

1.02 (0.65–1.57)

1.01 (0.6–1.5)

1.3 (0.65–1.83)

0.59

ICU mortality

22 (42.3%)

11 (35.4%)

11 (55.5%)

0.05

  1. Data shown as median (25%–75%), except for ICU mortality which is shown as absolute n (%). ECLT: Euglobulin Clot Lysis Time; WBC: White blood cells; SOFA: sequential organ failure assessment; SAPS: simplified acute physiology score; vWF: von Willebrand factor