Table 1 Baseline characteristics of patients with acute myocardial infarction (n = 112)

TF Activity, (pmol)

7.0 ± 0.90

54.2 ± 3.30

<0.001

TF Activity + anti TFPI, (pmol)

39.7 ± 2.25

65.8 ± 2.99

<0.001

Demographics

   Median age, years

64.5 ± 1.54

58.7 ± 1.95

0.02

   Male sex

54 (84.4%)

37 (77.1%)

1.0

   Number of CV death (n)

5 (7.8%)

11 (22.9%)

0.02

   Time to death (days)

437.3 ± 145.72

218.0 ± 55.63

0.68

   Days of follow up (days)

1460.0 ± 0.0

1460.0 ± 0.0

1.0

Pevious medical history

   Myocardial infarction

15 (24.4%)

8 (16.7%)

0.005

   ACVB

5 (7.8%)

2 (4.2%)

0.001

Cardiovascular risk factors

   Arterial hypertension

40 (62.5%)

34 (70.8%)

0.17

   Diabetes mellitus

14 (21.9%)

15 (31.3%)

0.001

   Hypercholesterolemia

39 (60.9%)

25 (52.1%)

0.41

   Current smoker

42 (65.6%)

36 (75.0%)

0.001

Biochemical markers

   Peak creatine kinase, U/l

1475.0 ± 357.91

1897.7 ± 276.5

0.03

   C-reactive protein, mg/dl

44.7 ± 11.22

26.2 ± 6.79

0.25

   NT-pro-BNP, pg/ml

1739.4 ± 402.93

3946.8 ± 1442.53

0.28

Clinical data

   Prehospital CPR

5 (7.8%)

10 (20.8%)

0.05

   Cardiogenic shock

9 (14.1%)

13 (27.1%)

0.09

   Killip's class

I

47 (73.4%)

25 (52.1%)

0.04

II

8 (12.5%)

10 (20.8%)

0.09

III

3 (4.7%)

6 (12.5%)

0.60

IV

6 (9.4%)

7 (14.6%)

0.40

Angiographic data

   Left ventricular function

46.2 ± 1.56

45.3 ± 1.97

0.77

   Target vessel

LAD

27 (42.2%)

29 (60.4%)

0.30

RCA

30 (46.9%)

12 (25.0%)

0.03

LCx

7 (10.9%)

7 (14.6%)

0.57

   Extent of coronary artery

   Disease

1-vessel-disease

18 (28.1%)

15 (31.3%)

0.72

2-vessel-disease

18 (28.1%)

14 (29.2%)

0.29

3-vessel-disease

28 (43.8%)

19 (39.6%)

0.16

   Medication on admission

Aspirin

64 (100%)

48 (100%)

1.0

Heparin

12 (18.8%)

4 (8.3%)

0.07

Clopidogrel

54 (84.4%)

44 (91.7%)

0.83

Beta-Blockers

18 (28.1%)

10 (20.8%)

0.07

ACE-Inhibitors

10 (15.6%)

7 (14.6%)

0.86

Statins

12 (18.8%)

5 (10.4%)

0.85