From: Plasma TF activity predicts cardiovascular mortality in patients with acute myocardial infarction
Characteristic | TF activity ≤ 24 pmol (n = 106) | TF activity > 24 pmol (n = 68) | P |
---|---|---|---|
TF Activity, (pmol) | 7.39 ± 0.60 | 53.9 ± 2.76 | <0.001 |
TF Activity + anti TFPI, (pmol) | 41.36 ± 1.92 | 66.17 ± 2.38 | <0.001 |
Demographics | Â | Â | Â |
   Median age, years | 66.6 ± 1.05 | 67.2 ± 1.36 | 0.79 |
   Male sex | 76 (71.7%) | 37 (54.4%) | 0.88 |
   Number of CV death (n) | 10 (9.4%) | 5 (7.4%) |  |
   Time to death (days) | 655.47 ± 123.49 | 642.78 ± 137.90 | 0.93 |
   Days of follow up (days) | 1414.48 ± 11.24 | 1443.75 ± 8.39 | 0.13 |
Previous medical history | Â | Â | Â |
   Myocardial infarction | 35 (33.0%) | 21 (30.9%) | 0.74 |
   ACVB | 13 (12.3%) | 7 (10.3%) | 0.69 |
Cardiovascular risk factors | Â | Â | Â |
   Arterial hypertension | 91 (85.9%) | 56 (82.4%) | 0.54 |
   Diabetes mellitus | 28 (26.4%) | 28 (41.2%) | 0.07 |
   Hypercholesterolemia | 69 (65.1%) | 40 (58.8%) | 0.35 |
   Current smoker | 51 (48.1%) | 30 (44.1%) | 0.50 |
Biochemical markers | Â | Â | Â |
   Peak creatine kinase, U/l | 92.7 ± 5.39 | 188.2 ± 15.39 | 0.56 |
   C-reactive protein, mg/dl | 22.9 ± 4.00 | 24.8 ± 4.37 | 0.19 |
   NT-pro-BNP, pg/ml | 2321.24 ± 490.50 | 2176.1 ± 306.79 | 0.13 |
Clinical data | Â | Â | Â |
   Prehospital CPR | 1 (0.9%) | 1 (1.5%) | 0.75 |
   Cardiogenic shock | 2 (1.9%) | 0 (0.0%) | 0.26 |
   Killip's class |  |  |  |
I | 103 (97.2%) | 64 (94.1%) | 0.32 |
II | 2 (1.9%) | 1 (1.5%) | 0.84 |
III | 0 (0.0%) | 2 (2.9%) | 0.08 |
IV | 1 (0.9%) | 1 (1.5.%) | 0.75 |
Angiographic data | Â | Â | Â |
   Left ventricular function | 52.6 ± 1.38 | 51.5 ± 1.77 | 0.67 |
   Target vessel |  |  |  |
LAD | 44 (41.5%) | 33 (48.5%) | 0.27 |
RCA | 33 (31.1%) | 24 (35.3%) | 0.20 |
LCx | 29 (27.4%) | 11 (16.8%) | 0.14 |
   Extent of coronary artery |  |  |  |
   Disease |  |  |  |
1-vessel-disease | 21 (19.8%) | 13 (19.1%) | 0.90 |
2-vessel-disease | 32 (30.2%) | 21 (30.9%) | 0.76 |
3-vessel-disease | 53 (50.0%) | 34 (50.0%) | 0.85 |
   Medication on admission |  |  |  |
Aspirin | 106 (100%) | 68 (100.0%) | 1.00 |
Heparin | 63 (63.4%) | 38 (55.9%) | 0.79 |
Clopidogrel | 91 (85.8%) | 49 (72.1%) | 0.54 |
Beta-Blockers | 62 (58.5%) | 38 (55.8%) | 0.82 |
ACE-Inhibitors | 53 (50.0%) | 29 (42.7%) | 0.34 |
Statins | 44 (41.5%) | 24 (35.3%) | 0.46 |