TY - JOUR AU - Artang, Ramin AU - Frandsen, Niels J. AU - Nielsen, Jørn Dalsgaard PY - 2009 DA - 2009/11/10 TI - Application of basic and composite thrombelastography parameters in monitoring of the antithrombotic effect of the low molecular weight heparin dalteparin: an in vivo study JO - Thrombosis Journal SP - 14 VL - 7 IS - 1 AB - Low molecular weight heparin (LMWH) is in vast usage for treatment of thromboembolic diseases such as deep venous thrombosis and acute coronary syndromes. There are certain clinical situations where a quick point of care testing of the effect of LMWH would be useful. At this point there are no point of care devices available in the market for monitoring the effect of LMWH. Thrombelastography (TEG) evaluates the viscoelastic properties of blood during coagulation. The clinical application of TEG in monitoring LMWH treatment is not yet well defined. The purpose of this in vivo study was to systematically evaluate the most suitable TEG parameters for evaluation of the antithrombotic effect of LMWH. We furthermore evaluated for the first time the usefulness of the composite TEG parameter the Thrombodynamic Ratio (TDR) in monitoring LMWH treatment. SN - 1477-9560 UR - https://doi.org/10.1186/1477-9560-7-14 DO - 10.1186/1477-9560-7-14 ID - Artang2009 ER -