Thrombosis Journal

Table 3 Warfarin pharmacogenetic profile obtained in the fifty-eight individuals, carriers of at least one variation in F5 or F2 genes and one in MTHFR

From: Thrombotic genetic risk factors and warfarin pharmacogenetic variants in São Miguel's healthy population (Azores)

	Thrombotic risk factors				Warfarin pharmacogenetics
	F5	F2	MTHFR		CYP2C9		VKORC1
N (%)	1691G>A	20210G>A	677C>T	1298A>C	430C>T	1075A>C	1639G>A
1 (1.7)	G A	GG	TT	AA	TT	A C	G A
1 (1.7)	G A	GG	TT	AA	C T	A C	AA
1 (1.7)	GA	GG	CC	AC	CT	AC	GA
2 (3.5)	GA	GG	CT	AA	CT	AC	GA
1 (1.7)	GA	GG	CC	AC	CT	AC	GG
1 (1.7)	GG	GA	CT	AC	CC	AC	AA
1 (1.7)	GA	GG	CC	CC	CC	AC	GA
1 (1.7)	GA	GG	CT	AC	CC	AC	GA
1 (1.7)	GG	G A	TT	AA	CC	A C	G A
1 (1.7)	GA	GG	CC	AC	CC	AC	GG
2 (3.5)	GA	GG	CT	AA	CC	AC	GG
1 (1.7)	G A	GG	TT	CC	TT	AA	G A
1 (1.7)	GA	GG	CT	AA	CT	AA	AA
1 (1.7)	GA	GG	CT	AC	CT	AA	GA
1 (1.7)	G A	GG	TT	AA	C T	AA	G A
2 (3.5)	GG	GA	CT	AC	CT	AA	GA
1 (1.7)	GG	GA	CT	AA	CT	AA	GG
2 (3.5)	GA	GG	CT	AA	CT	AA	GG
1 (1.7)	G A	GG	TT	AA	C T	AA	GG
2 (3.5)	GA	GG	CC	AC	CC	AA	AA
1 (1.7)	GA	GG	CT	AA	CC	AA	AA
3 (5.2)	G A	GG	TT	AA	CC	AA	AA
1 (1.7)	GG	GA	CC	AC	CC	AA	AA
1 (1.7)	GG	GA	CT	AC	CC	AA	AA
1 (1.7)	GG	G A	TT	AA	CC	AA	AA
2 (3.5)	GA	GG	CC	AC	CC	AA	GA
1 (1.7)	GA	GG	CT	AA	CC	AA	GA
2 (3.5)	GA	GG	CT	AC	CC	AA	GA
4 (6.9)	G A	GG	TT	AA	CC	AA	G A
1 (1.7)	GG	AA	CC	AC	CC	AA	GA
1 (1.7)	GG	GA	CC	AC	CC	AA	GA
1 (1.7)	GG	GA	CC	CC	CC	AA	GA
2 (3.5)	GG	GA	CT	AA	CC	AA	GA
2 (3.5)	GA	GG	CC	AC	CC	AA	GG
3 (5.2)	GA	GG	CT	AA	CC	AA	GG
2 (3.5)	GA	GG	CT	AC	CC	AA	GG
1 (1.7)	GG	GA	CC	CC	CC	AA	GG
1 (1.7)	GG	GA	CT	AA	CC	AA	GG
3 (5.2)	G A	GG	TT	AA	CC	AA	GG

Italic characters indicate nucleotide changes considering the wild-type allele and in bold illustrate carriers of the F5 G1691A or F2 G20210A with MTHFR 677TT genotype conferring high thrombotic risk.

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ISSN: 1477-9560

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