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Table 1 Lung inflammation measurements

From: Development and comparison of a minimally-invasive model of autologous clot pulmonary embolism in Sprague-Dawley and Copenhagen rats

Parameter Time Sprague-Dawley Copenhagen
   PE Sham Sig. PE Sham Sig
Weight (g) 24 hr 399 ± 5 392 ± 4 n.s. 240 ± 8 254 ± 2 n.s.
  5 day 402 ± 5 393 ± 5 n.s. 244 ± 8 245 ± 4 n.s.
Pleural WBC (×105) 24 hr 108 ± 19 109 ± 32 n.s. 27 ± 4 32 ± 4 n.s.
  5 day 107 ± 16 109 ± 4 n.s. 39 ± 8 31 ± 3 n.s.
BAL WBC (×103) 24 hr 543 ± 45 337 ± 35 * 491 ± 26 415 ± 51 n.s.
  5 day 587 ± 82 514 ± 40 n.s. 449 ± 65 435 ± 44 n.s.
BAL Chemotaxis (×103) 24 hr 52 ± 9 33 ± 3 n.s. 16 ± 1 17 ± 2 n.s.
  5 day 41 ± 4 37 ± 4 n.s. 18 ± 2 13 ± 5 n.s.
BAL MPO (U/mL) 24 hr 229 ± 79 104 ± 23 n.s. 128 ± 11 152 ± 57 n.s.
  5 day 256 ± 133 301 ± 65 n.s. 142 ± 87 102 ± 19 n.s.
BAL MCP-1 (pg/mL) 24 hr 137 ± 90 42 ± 14 n.s. 188 ± 112 134 ± 48 n.s.
  5 day 24 ± 13 101 ± 80 n.s. 187 ± 105 228 ± 59 n.s.
BAL CINC-1 (pg/mL) 24 hr 62 ± 32 32 ± 11 n.s. 66 ± 14 38 ± 12 n.s.
  5 day 21 ± 6 30 ± 12 n.s. 36 ± 8 41 ± 7 n.s.
BAL CINC-2 (pg/mL) 24 hr 638 ± 51 554 ± 32 n.s. 267 ± 23 220 ± 28 n.s.
  5 day 610 ± 45 552 ± 40 n.s. 266 ± 42 280 ± 18 n.s.
BAL CINC-3 (pg/mL) 24 hr 21 ± 1 21 ± 0.4 n.s. 19 ± 4 19 ± 8 n.s.
  5 day 20 ± 0.3 20 ± 0.1 n.s. 18 ± 6 15 ± 4 n.s.
  1. Values are mean ± standard error, where n = 10 Sprague-Dawley, n = 4-5 Copenhagen. *Indicates a value significantly different from vehicle-treated Sham animals (Bonferroni-adjusted p < 0.05, t-Test). Abbreviations: not significant (n.s.); pleural white blood cell count (WBC); bronchoalveolar lavage fluid (BAL); white blood cell count (WBC); in vitro neutrophil chemotaxis in response to BAL fluid (Chemotaxis) myeloperoxidase activity (MPO); monocyte chemotactic factor (MCP); cytokine-induced neutrophil chemotactic factor (CINC).